Enhancing the Therapeutic Effects of Ethyl Pyruvate on Gastric Cancer through Knockdown of YAP1 Expression

Yes-associated protein (YAP) plays a critical role in tumor formation and malignancy of many cancers and has been shown to be the important therapeutic target. Ethyl pyruvate (EP), a stable lipophilic pyruvate derivative, is a potent inhibitor of high mobility group box-B1 (HMGB1) release and exerts...

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Bibliographic Details
Main Authors: J. Zhang, J-S. Zhu, Y-C. Yang, Z. Zhou, W-X. Chen, N-W. Chen
Format: Article
Language:English
Published: SAGE Publishing 2013-01-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/1721727X1301100112