Enhancing the Therapeutic Effects of Ethyl Pyruvate on Gastric Cancer through Knockdown of YAP1 Expression
Yes-associated protein (YAP) plays a critical role in tumor formation and malignancy of many cancers and has been shown to be the important therapeutic target. Ethyl pyruvate (EP), a stable lipophilic pyruvate derivative, is a potent inhibitor of high mobility group box-B1 (HMGB1) release and exerts...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2013-01-01
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Series: | European Journal of Inflammation |
Online Access: | https://doi.org/10.1177/1721727X1301100112 |