CD45dimCD34+CD38−CD133+ cells have the potential as leukemic stem cells in acute myeloid leukemia

CD45dimCD34+CD38−CD133+ cells have the potential as leukemic stem cells in acute myeloid leukemia

Abstract Background Leukemia stem cells (LSCs) in play an important role in the initiation, relapse, and progression of acute myeloid leukemia (AML), and in the development of chemotherapeutic drug resistance in AML. Studies regarding the detection of LSCs and the development of novel therapies for...

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Bibliographic Details
Main Authors: Sook-Kyoung Heo, Eui-Kyu Noh, Lan Jeong Ju, Jun Young Sung, Yoo Kyung Jeong, Jaekyung Cheon, Su Jin Koh, Young Joo Min, Yunsuk Choi, Jae-Cheol Jo
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Cancer
Subjects:
Acute myeloid leukemia
Leukemic stem cells
CD45dimCD34+CD38−CD133+ cells
Prognosis
Immunophenotyping
Online Access:http://link.springer.com/article/10.1186/s12885-020-06760-1

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http://link.springer.com/article/10.1186/s12885-020-06760-1

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