Evaluation of Nucleoside Analogs as Antimicrobials Targeting Unique Enzymes in <i>Borrelia burgdorferi</i>

The first line therapy for Lyme disease is treatment with doxycycline, amoxicillin, or cefuroxime. In endemic regions, the persistence of symptoms in many patients after completion of antibiotic treatment remains a major healthcare concern. The causative agent of Lyme disease is a spirochete, <i&...

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Bibliographic Details
Main Authors: Monideep Chakraborti, Samantha Schlachter, Shekerah Primus, Julie Wagner, Brandi Sweet, Zoey Carr, Kenneth A. Cornell, Nikhat Parveen
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Pathogens
Subjects:
Bgp
Pfs
Online Access:https://www.mdpi.com/2076-0817/9/9/678