Human Placental Syncytiotrophoblasts Restrict Toxoplasma gondii Attachment and Replication and Respond to Infection by Producing Immunomodulatory Chemokines

Toxoplasma gondii is a major source of congenital disease worldwide, but the cellular and molecular factors associated with its vertical transmission are largely unknown. In humans, the placenta forms the key interface between the maternal and fetal compartments and forms the primary barrier that re...

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Bibliographic Details
Main Authors: Stephanie E. Ander, Elizabeth N. Rudzki, Nitin Arora, Yoel Sadovsky, Carolyn B. Coyne, Jon P. Boyle, John C. Boothroyd
Format: Article
Language:English
Published: American Society for Microbiology 2018-01-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/9/1/e01678-17