Comparison of two ASC-derived therapeutics in an in vitro OA model: secretome versus extracellular vesicles
Abstract Background In the last years, several clinical trials have proved the safety and efficacy of adipose-derived stem/stromal cells (ASC) in contrasting osteoarthritis (OA). Since ASC act mainly through paracrine mechanisms, their secretome (conditioned medium, CM) represents a promising therap...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-12-01
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Series: | Stem Cell Research & Therapy |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13287-020-02035-5 |