Correlations Between MRI Biomarkers PDFF and cT1 With Histopathological Features of Non-Alcoholic Steatohepatitis

Correlations Between MRI Biomarkers PDFF and cT1 With Histopathological Features of Non-Alcoholic Steatohepatitis

IntroductionLate stage clinical trials in non-alcoholic steatohepatitis (NASH) are currently required by the FDA to use liver biopsy as a primary endpoint. The well-reported limitations with biopsy, such as associated risks and sampling error, coupled with patient preference, are driving investigati...

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Bibliographic Details
Main Authors: Andrea Dennis, Matt D. Kelly, Carolina Fernandes, Sofia Mouchti, Jonathan A. Fallowfield, Gideon Hirschfield, Michael Pavlides, Stephen Harrison, Manu V. Chakravarthy, Rajarshi Banerjee, Arun Sanyal
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Endocrinology
Subjects:
imaging
NASH
NAFLD
non-invasive biomarkers
MRI
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2020.575843/full

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https://www.frontiersin.org/articles/10.3389/fendo.2020.575843/full

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