Palmitate but Not Oleate Exerts a Negative Effect on Oxygen Utilization in Myoblasts of Patients with the m.3243A>G Mutation: A Pilot Study

It is known that exposure to excess saturated fatty acids, especially palmitate, can trigger cellular stress responses interpreted as lipotoxicity. The effect of excessive free fatty acids on oxidative phosphorylation capacity in myoblasts of patients with the m.3243A>G mutation was evaluated wit...

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Bibliographic Details
Main Authors: Leila Motlagh Scholle, Helena Schieffers, Samiya Al-Robaiy, Annemarie Thaele, Diana Lehmann Urban, Stephan Zierz
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/10/9/204