A Tridimensional Model for NK Cell-Mediated ADCC of Follicular Lymphoma

A Tridimensional Model for NK Cell-Mediated ADCC of Follicular Lymphoma

Follicular lymphoma (FL) is the second most frequent subtype of B non-Hodgkin's lymphomas (NHL) for which the treatment is based on the use of anti-CD20 mAbs. NK cells play a crucial role in their mechanism of action and the number of these cells mediating antibody-dependent cell cycotoxicity (...

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Bibliographic Details
Main Authors: Emilie Decaup, Cédric Rossi, Pauline Gravelle, Camille Laurent, Julie Bordenave, Marie Tosolini, Anne Tourette, Emeline Perrial, Charles Dumontet, Mary Poupot, Christian Klein, Ariel Savina, Jean-Jacques Fournié, Christine Bezombes
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
ADCC—antibody dependent cellular cytotoxicity
NK cells
modelization
3D co-culture model
follicular lymphoma
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01943/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01943/full

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