Dereplication Guided Discovery of Secondary Metabolites of Mixed Biosynthetic Origin from Aspergillus aculeatus

Dereplication Guided Discovery of Secondary Metabolites of Mixed Biosynthetic Origin from Aspergillus aculeatus

Investigation of the chemical profile of the industrially important black filamentous fungus Aspergillus aculeatus by UHPLC-DAD-HRMS and subsequent dereplication has led to the discovery of several novel compounds. Isolation and extensive 1D and 2D NMR spectroscopic analyses allowed for structural e...

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Bibliographic Details
Main Authors: Lene M. Petersen, Casper Hoeck, Jens C. Frisvad, Charlotte H. Gotfredsen, Thomas O. Larsen
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:Molecules
Subjects:
Aspergillus aculeatus
Aspergilli
natural products
secondary metabolism
dereplication
sclerotia
Online Access:http://www.mdpi.com/1420-3049/19/8/10898

Internet

http://www.mdpi.com/1420-3049/19/8/10898

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