Acute myeloid leukemia immunopeptidome reveals HLA presentation of mutated nucleophosmin.

Acute myeloid leukemia immunopeptidome reveals HLA presentation of mutated nucleophosmin.

Somatic mutations in cancer are a potential source of cancer specific neoantigens. Acute myeloid leukemia (AML) has common recurrent mutations shared between patients in addition to private mutations specific to individuals. We hypothesized that neoantigens derived from recurrent shared mutations wo...

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Bibliographic Details
Main Authors: Rupa Narayan, Niclas Olsson, Lisa E Wagar, Bruno C Medeiros, Everett Meyer, Debra Czerwinski, Michael S Khodadoust, Lichao Zhang, Liora Schultz, Mark M Davis, Joshua E Elias, Ron Levy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219547

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https://doi.org/10.1371/journal.pone.0219547

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