Síntese e avaliação da atividade antimalárica de compostos derivados da curcumina

Síntese e avaliação da atividade antimalárica de compostos derivados da curcumina

One of the main challenges in the development of new antimalarial drugs is to achieve a viable lead candidate with good pharmacokinetic properties. Curcumin has a broad range of biological activities, including antimalarial activity. Herein, we report the antimalarial activity of six curcumin deriva...

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Bibliographic Details
Main Authors: Patrícia Ramos Gomes, Fábio Balbino Miguel, Michael Éder de Oliveira, Vanessa Viana Ferreira, Daniel Silqueira Martins Guimarães, Aline Brito de Lima, Camila de Souza Barbosa, Mariana Amorim de Oliveira, Mauro Vieira de Almeida, Gustavo Henrique Ribeiro Viana, Mara Rubia Costa Couri, Fernando de Pilla Varotti
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2014-06-01
Series:Química Nova
Subjects:
curcumin derivatives
antimalarial chemotherapy
Plasmodium falciparum
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000300018&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000300018&lng=en&tlng=en

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