Effect of acute hypobaric hypoxia on the endothelial glycocalyx and digital reactive hyperemia in humans

Effect of acute hypobaric hypoxia on the endothelial glycocalyx and digital reactive hyperemia in humans

Introduction: Hypoxia is associated with increased capillary permeability. This study tested whether acute hypobaric hypoxia involves degradation of the endothelial glycocalyx. Methods: We exposed 12 subjects to acute hypobaric hypoxia (equivalent to 4,500 m for 2-4 hours) and measured venous blood...

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Bibliographic Details
Main Authors: Pär I Johansson, Anita eBergström, Niels Jacob eAachmann-Andersen, Martin A.S. Meyer, Sisse Rye Ostrowski, Nikolai B. Nordsborg, Niels Vidiendal eOlsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Physiology
Subjects:
Endothelium, Vascular
Glycocalyx
Hypoxia, Brain
Nitrates
Syndecan-1
arterial tonometry
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00459/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00459/full

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