PPARγ Is Activated during Congenital Cytomegalovirus Infection and Inhibits Neuronogenesis from Human Neural Stem Cells.

PPARγ Is Activated during Congenital Cytomegalovirus Infection and Inhibits Neuronogenesis from Human Neural Stem Cells.

Congenital infection by human cytomegalovirus (HCMV) is a leading cause of permanent sequelae of the central nervous system, including sensorineural deafness, cerebral palsies or devastating neurodevelopmental abnormalities (0.1% of all births). To gain insight on the impact of HCMV on neuronal deve...

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Bibliographic Details
Main Authors: Maude Rolland, Xiaojun Li, Yann Sellier, Hélène Martin, Teresa Perez-Berezo, Benjamin Rauwel, Alexandra Benchoua, Bettina Bessières, Jacqueline Aziza, Nicolas Cenac, Minhua Luo, Charlotte Casper, Marc Peschanski, Daniel Gonzalez-Dunia, Marianne Leruez-Ville, Christian Davrinche, Stéphane Chavanas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005547

Internet

https://doi.org/10.1371/journal.ppat.1005547

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