The application of NIPT using combinatorial probe-anchor synthesis to identify sex chromosomal aneuploidies (SCAs) in a cohort of 570 pregnancies

The application of NIPT using combinatorial probe-anchor synthesis to identify sex chromosomal aneuploidies (SCAs) in a cohort of 570 pregnancies

Abstract Background Non-invasive prenatal testing (NIPT) as alternative screening method had been proven to have very high sensitivity and specificity for detecting common aneuploidies such as T21, T18, and T13, with low false positive and false negative rates. Unfortunately, recent studies suggeste...

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Bibliographic Details
Main Authors: Hongge Li, Yu Lei, Hui Zhu, Yuqin Luo, Yeqing Qian, Min Chen, Yixi Sun, Kai Yan, Yanmei Yang, Bei Liu, Liya Wang, Yingzhi Huang, Junjie Hu, Jianyun Xu, Minyue Dong
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Molecular Cytogenetics
Subjects:
Non-invasive prenatal testing (NIPT)
Sex chromosomal aneuploidies (SCAs)
Combinatorial probe-anchor synthesis (CPAS)
Online Access:http://link.springer.com/article/10.1186/s13039-018-0407-z

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http://link.springer.com/article/10.1186/s13039-018-0407-z

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