RIPK1-Associated Inborn Errors of Innate Immunity

RIPK1-Associated Inborn Errors of Innate Immunity

RIPK1 (receptor-interacting serine/threonine-protein kinase 1) is a key molecule for mediating apoptosis, necroptosis, and inflammatory pathways downstream of death receptors (DRs) and pattern recognition receptors (PRRs). RIPK1 functions are regulated by multiple post-translational modifications (P...

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Bibliographic Details
Main Authors: Jiahui Zhang, Taijie Jin, Ivona Aksentijevich, Qing Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
RIPK1
programmed cell death
immunodeficiency
autoinflammatory disease
CRIA
biological therapies
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.676946/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.676946/full

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