A novel DNA methylation panel accurately detects colorectal cancer independently of molecular pathway

A novel DNA methylation panel accurately detects colorectal cancer independently of molecular pathway

Abstract Background Colorectal cancer (CRC) is one of the most incident cancers, associated with significant morbidity and mortality, and usually classified into three main molecular pathways: chromosomal instability, microsatellite instability (MSI) and CpG island methylator phenotype (CIMP). Curre...

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Bibliographic Details
Main Authors: Micaela Freitas, Fábio Ferreira, Sónia Carvalho, Fernanda Silva, Paula Lopes, Luís Antunes, Sofia Salta, Francisca Diniz, Lúcio Lara Santos, José Flávio Videira, Rui Henrique, Carmen Jerónimo
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Journal of Translational Medicine
Subjects:
Colorectal cancer
Gene promoter methylation
Biomarkers
Diagnosis
Prognosis
Online Access:http://link.springer.com/article/10.1186/s12967-018-1415-9

Internet

http://link.springer.com/article/10.1186/s12967-018-1415-9

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