Optimization of a Culture Medium for Increased Mevinolin Production by Aspergillus terreus Strain
Fungi are important sources for the production of some pharmaceutical compounds. e.g. lovastatin, mevinolin and monacolin K. These are competitive inhibitors of 3-hydroxy-3-methyl glutaryl coenzyme A reductase, the rate limiting enzyme of cholesterol synthesis pathway. Four fungal strains of Aspergi...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Malaysian Society for Microbiology
2008-01-01
|
Series: | Malaysian Journal of Microbiology |
Subjects: | |
Online Access: | http://web.usm.my/mjm/issues/vol4no2/research2.pdf |