Optimization of a Culture Medium for Increased Mevinolin Production by Aspergillus terreus Strain

Fungi are important sources for the production of some pharmaceutical compounds. e.g. lovastatin, mevinolin and monacolin K. These are competitive inhibitors of 3-hydroxy-3-methyl glutaryl coenzyme A reductase, the rate limiting enzyme of cholesterol synthesis pathway. Four fungal strains of Aspergi...

Full description

Bibliographic Details
Main Authors: Atalla, M. M., Hamed, E. R., El-Shami, A. R.
Format: Article
Language:English
Published: Malaysian Society for Microbiology 2008-01-01
Series:Malaysian Journal of Microbiology
Subjects:
Online Access:http://web.usm.my/mjm/issues/vol4no2/research2.pdf