In vivo efficacy of the histone deacetylase inhibitor suberoylanilide hydroxamic acid in combination with radiotherapy in a malignant rhabdoid tumor mouse model

In vivo efficacy of the histone deacetylase inhibitor suberoylanilide hydroxamic acid in combination with radiotherapy in a malignant rhabdoid tumor mouse model

<p>Abstract</p> <p>Purpose</p> <p>Histone deacetylase inhibitors are promising new substances in cancer therapy and have also been shown to sensitize different tumor cells to irradiation (XRT). We explored the effect as well as the radiosensitizing properties of suberoy...

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Bibliographic Details
Main Authors: Thiemann Markus, Oertel Susanne, Ehemann Volker, Weichert Wilko, Stenzinger Albrecht, Bischof Marc, Weber Klaus-J, Perez Ramon, Haberkorn Uwe, Kulozik Andreas E, Debus Jürgen, Huber Peter E, Battmann Claudia
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Radiation Oncology
Subjects:
Malignant rhabdoid tumor
In vivo
Radiotherapy
Histone deacetylase inhibition
Suberoylanilide hydroxamic acid
Online Access:http://www.ro-journal.com/content/7/1/52

Internet

http://www.ro-journal.com/content/7/1/52

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