DNA unwinding by ring-shaped T4 helicase gp41 is hindered by tension on the occluded strand.

The replicative helicase for bacteriophage T4 is gp41, which is a ring-shaped hexameric motor protein that achieves unwinding of dsDNA by translocating along one strand of ssDNA while forcing the opposite strand to the outside of the ring. While much study has been dedicated to the mechanism of bind...

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Bibliographic Details
Main Authors: Noah Ribeck, Omar A Saleh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3826741?pdf=render