Haloperidol treatment reverses behavioural and anatomical changes in cocaine-dependent mice

Haloperidol treatment reverses behavioural and anatomical changes in cocaine-dependent mice

Abnormal dopamine (DA) transmission occurs in many pathological conditions, including drug addiction. Previously, we showed DA D2 receptor (D2R) activation results in pruning of the axonal arbour of DA neurones that innervate the dorsal striatum. Thus, we hypothesised that long-term D2R stimulation...

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Bibliographic Details
Main Authors: C.L. Parish, J. Drago, D. Stanic, E. Borrelli, D.I. Finkelstein, M.K. Horne
Format: Article
Language:English
Published: Elsevier 2005-06-01
Series:Neurobiology of Disease
Subjects:
Addiction
Dopamine
Cocaine
Haloperidol
Stereology
Behaviour
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105000239

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http://www.sciencedirect.com/science/article/pii/S0969996105000239

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