Impact of Population Stratification on Family-Based Association in an Admixed Population

Population substructure is a well-known confounder in population-based case-control genetic studies, but its impact in family-based studies is unclear. We performed population substructure analysis using extended families of admixed population to evaluate power and Type I error in an association stu...

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Bibliographic Details
Main Authors: T. B. Mersha, L. Ding, H. He, E. S. Alexander, X. Zhang, B. G. Kurowski, V. Pilipenko, L. Kottyan, L. J. Martin, D. W. Fardo
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:International Journal of Genomics
Online Access:http://dx.doi.org/10.1155/2015/501617