Prostate cancer risk is not altered by TP53AIP1 germline mutations in a German case-control series.

Prostate cancer susceptibility has previously been associated with truncating germline variants in the gene TP53AIP1 (tumor protein p53 regulated apoptosis inducing protein 1). For two apparently recurrent mutations (p.Q22fs and p.S32X) a remarkable OR of 5.1 was reported for prostate cancer risk. S...

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Bibliographic Details
Main Authors: Manuel Luedeke, Irina Coinac, Carmen M Linnert, Natalia Bogdanova, Antje E Rinckleb, Mark Schrader, Walther Vogel, Josef Hoegel, Andreas Meyer, Thilo Dörk, Christiane Maier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3311578?pdf=render