GDNF to the rescue: GDNF delivery effects on motor neurons and nerves, and muscle re-innervation after peripheral nerve injuries

GDNF to the rescue: GDNF delivery effects on motor neurons and nerves, and muscle re-innervation after peripheral nerve injuries

Peripheral nerve injuries commonly occur due to trauma, like a traffic accident. Peripheral nerves get severed, causing motor neuron death and potential muscle atrophy. The current golden standard to treat peripheral nerve lesions, especially lesions with large (≥ 3 cm) nerve gaps, is the use of a n...

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Bibliographic Details
Main Authors: Alberto F Cintron-Colon, Gabriel Almeida-Alves, Juliana M VanGyseghem, John M Spitsbergen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Neural Regeneration Research
Subjects:
electrical muscle stimulation; exercise; glial cell line-derived neurotrophic factor; glial cell line-derived neurotrophic factor delivery; motor neuron; nerve gap; neurotrophic factor; peripheral nerve injury; schwann cells; skeletal muscle atrophy
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=4;spage=748;epage=753;aulast=

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=4;spage=748;epage=753;aulast=

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