Positive radionuclide imaging of miRNA expression using RILES and the human sodium iodide symporter as reporter gene is feasible and supports a protective role of miRNA-23a in response to muscular atrophy.

Positive radionuclide imaging of miRNA expression using RILES and the human sodium iodide symporter as reporter gene is feasible and supports a protective role of miRNA-23a in response to muscular atrophy.

MicroRNAs (miRNAs) are key players in many biological processes and are considered as an emerging class of pharmacology drugs for diagnosis and therapy. However to fully exploit the therapeutic potential of miRNAs, it is becoming crucial to monitor their expression pattern using medical imaging moda...

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Bibliographic Details
Main Authors: Viorel Simion, Julien Sobilo, Rudy Clemoncon, Sharuja Natkunarajah, Safia Ezzine, Florence Abdallah, Stephanie Lerondel, Chantal Pichon, Patrick Baril
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5426778?pdf=render

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http://europepmc.org/articles/PMC5426778?pdf=render

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