Effects of prolonged exposure to hypobaric hypoxia on oxidative stress, inflammation and gluco-insular regulation: the not-so-sweet price for good regulation.

Effects of prolonged exposure to hypobaric hypoxia on oxidative stress, inflammation and gluco-insular regulation: the not-so-sweet price for good regulation.

The mechanisms by which low oxygen availability are associated with the development of insulin resistance remain obscure. We thus investigated the relationship between such gluco-insular derangements in response to sustained (hypobaric) hypoxemia, and changes in biomarkers of oxidative stress, infla...

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Bibliographic Details
Main Authors: Mario Siervo, Heather L Riley, Bernadette O Fernandez, Carl A Leckstrom, Daniel S Martin, Kay Mitchell, Denny Z H Levett, Hugh E Montgomery, Monty G Mythen, Michael P W Grocott, Martin Feelisch, Caudwell Xtreme Everest Research Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3986261?pdf=render

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http://europepmc.org/articles/PMC3986261?pdf=render

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