An integrated transcriptomic and meta-analysis of hepatoma cells reveals factors that influence susceptibility to HCV infection.

Hepatitis C virus (HCV) is a global problem. To better understand HCV infection researchers employ in vitro HCV cell-culture (HCVcc) systems that use Huh-7 derived hepatoma cells that are particularly permissive to HCV infection. A variety of hyper-permissive cells have been subcloned for this purpo...

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Bibliographic Details
Main Authors: Jamie I MacPherson, Ben Sidders, Stefan Wieland, Jin Zhong, Paul Targett-Adams, Volker Lohmann, Perdita Backes, Oona Delpuech-Adams, Francis Chisari, Marilyn Lewis, Tanya Parkinson, David L Robertson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22046242/pdf/?tool=EBI