Genetic Variation in Complex Traits in Transgenic α-Synuclein Strains of <i>Caenorhabditis elegans</i>
Different genetic backgrounds can modify the effect of mutated genes. Human α-synuclein (<i>SNCA</i>) gene encodes α-synuclein, and its oligomeric complexes accumulate with age and mediate the disruption of cellular homeostasis, resulting in the neuronal death that is characteristic of P...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-07-01
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| Series: | Genes |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4425/11/7/778 |