Crystal structure of a tripartite complex between C3dg, C-terminal domains of factor H and OspE of Borrelia burgdorferi.

Crystal structure of a tripartite complex between C3dg, C-terminal domains of factor H and OspE of Borrelia burgdorferi.

Complement is an important part of innate immunity. The alternative pathway of complement is activated when the main opsonin, C3b coats non-protected surfaces leading to opsonisation, phagocytosis and cell lysis. The alternative pathway is tightly controlled to prevent autoactivation towards host ce...

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Bibliographic Details
Main Authors: Robert Kolodziejczyk, Kornelia M Mikula, Tommi Kotila, Vincent L G Postis, T Sakari Jokiranta, Adrian Goldman, Taru Meri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5708776?pdf=render

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http://europepmc.org/articles/PMC5708776?pdf=render

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