Residues at the tip of the pore loop of NR3B-containing NMDA receptors determine Ca<sup>2+ </sup>permeability and Mg<sup>2+ </sup>block

<p>Abstract</p> <p>Background</p> <p>Members of the complex N-methyl-D-aspartate receptor (NMDAR) subfamily of ionotropic glutamate receptors (iGluRs) conventionally assemble from NR1 and NR2 subunits, the composition of which determines receptor properties. Hallmark fe...

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Bibliographic Details
Main Authors: Orth Angela, Cavara Nora A, Hicking Gordon, Seebohm Guiscard, Hollmann Michael
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/11/133