Cibinetide Protects Isolated Human Islets in a Stressful Environment and Improves Engraftment in the Perspective of Intra Portal Islet Transplantation

Cibinetide Protects Isolated Human Islets in a Stressful Environment and Improves Engraftment in the Perspective of Intra Portal Islet Transplantation

During intra-portal pancreatic islet transplantation (PITx), innate immune reactions such as the instant blood mediated inflammatory reaction (IBMIR) cause an immediate loss of islets. The non-hematopoietic erythropoietin analogue cibinetide has previously shown islet-protective effects in mouse PIT...

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Bibliographic Details
Main Authors: Ming Yao, Anna Domogatskaya, Nils Ågren1, Masaaki Watanabe, Kazuaki Tokodai, Michael Brines, Anthony Cerami, Bo-Göran Ericzon, Makiko Kumagai-Braesch, Torbjörn Lundgren
Format: Article
Language:English
Published: SAGE Publishing 2021-08-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/09636897211039739

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https://doi.org/10.1177/09636897211039739

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