The gut microbiota instructs the hepatic endothelial cell transcriptome

The gut microbiota instructs the hepatic endothelial cell transcriptome

Summary: The gut microbiota affects remote organ functions but its impact on organotypic endothelial cell (EC) transcriptomes remains unexplored. The liver endothelium encounters microbiota-derived signals and metabolites via the portal circulation. To pinpoint how gut commensals affect the hepatic...

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Bibliographic Details
Main Authors: Henning Formes, Joana P. Bernardes, Amrit Mann, Franziska Bayer, Giulia Pontarollo, Klytaimnistra Kiouptsi, Katrin Schäfer, Sebastian Attig, Teodora Nikolova, Thomas G. Hofmann, Jörn M. Schattenberg, Hristo Todorov, Susanne Gerber, Philip Rosenstiel, Tobias Bopp, Felix Sommer, Christoph Reinhardt
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:iScience
Subjects:
Hepatology
Microbiome
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221010609

Internet

http://www.sciencedirect.com/science/article/pii/S2589004221010609

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