Preclinical evaluation of PSMA expression in response to androgen receptor blockade for theranostics in prostate cancer

Preclinical evaluation of PSMA expression in response to androgen receptor blockade for theranostics in prostate cancer

Abstract Background Prostate-specific membrane antigen (PSMA)-directed radioligand therapy (RLT) is a promising yet not curative approach in castration-resistant (CR) prostate cancer (PC). Rational combination therapies may improve treatment efficacy. Here, we explored the effect of androgen recepto...

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Bibliographic Details
Main Authors: Katharina Lückerath, Liu Wei, Wolfgang P. Fendler, Susan Evans-Axelsson, Andreea D. Stuparu, Roger Slavik, Christine E. Mona, Jeremie Calais, Matthew Rettig, Robert E. Reiter, Ken Herrmann, Caius G. Radu, Johannes Czernin, Matthias Eiber
Format: Article
Language:English
Published: SpringerOpen 2018-10-01
Series:EJNMMI Research
Subjects:
PSMA
Prostate cancer
68Ga-PSMA PET/CT
Androgen receptor blockade
Radioligand therapy
Online Access:http://link.springer.com/article/10.1186/s13550-018-0451-z

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http://link.springer.com/article/10.1186/s13550-018-0451-z

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