Hemodynamic and biological correlates of glomerular hyperfiltration in sickle cell patients before and under renin–angiotensin system blocker

Hemodynamic and biological correlates of glomerular hyperfiltration in sickle cell patients before and under renin–angiotensin system blocker

Abstract Glomerular hyperfiltration alone or associated with albuminuria is a well-known feature of sickle cell associated nephropathy. Though, glomerular hyperfiltration is currently considered to be related to a high renal plasma flow and chronic hemolysis, cardiac output influence on measured glo...

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Bibliographic Details
Main Authors: Jean-Philippe Haymann, Nadjib Hammoudi, Marine Livrozet, Aline Santin, Sarah Mattioni, Emmanuel Letavernier, Vincent Frochot, Camille Saint Jacques, Olivier Steichen, Gilles Grateau, Michel Chaignon, François Lionnet
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91161-y

Internet

https://doi.org/10.1038/s41598-021-91161-y

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