Abelmoschus esculentus subfractions attenuate Aβ and tau by regulating DPP-4 and insulin resistance signals

Abelmoschus esculentus subfractions attenuate Aβ and tau by regulating DPP-4 and insulin resistance signals

Abstract Background Insulin resistance could be associated with the development of Alzheimer disease (AD). The neuropathological hallmarks of AD are beta amyloid (Aβ) produced from sequential cleavage initiated by β-secretase and degraded by insulin degradation enzyme (IDE), as well as hyperphosphor...

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Bibliographic Details
Main Authors: Chien-Ning Huang, Chau-Jong Wang, Chih-Li Lin, Hsin-Hua Li, An-Ting Yen, Chiung-Huei Peng
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Abelmoschus esculentus
Beta amyloid
Insulin resistance
Dipeptidyl peptidase-4
Online Access:https://doi.org/10.1186/s12906-020-03163-4

Internet

https://doi.org/10.1186/s12906-020-03163-4

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