Inflammatory Determinants of Differential Tuberculosis Risk in Pre-Adolescent Children and Young Adults

Inflammatory Determinants of Differential Tuberculosis Risk in Pre-Adolescent Children and Young Adults

The risk of progression from Mycobacterium tuberculosis (M.tb) infection to active tuberculosis (TB) disease varies markedly with age. TB disease is significantly less likely in pre-adolescent children above 4 years of age than in very young children or post-pubescent adolescents and young adults. W...

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Bibliographic Details
Main Authors: Richard Baguma, Stanley Kimbung Mbandi, Miguel J. Rodo, Mzwandile Erasmus, Jonathan Day, Lebohang Makhethe, Marwou de Kock, Michele van Rooyen, Lynnett Stone, Nicole Bilek, Marcia Steyn, Hadn Africa, Fatoumatta Darboe, Novel N. Chegou, Gerard Tromp, Gerhard Walzl, Mark Hatherill, Adam Penn-Nicholson, Thomas J. Scriba
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
inflammation
tuberculosis
anti-mycobacterial immunity
age
pediatric
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.639965/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.639965/full

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