Intracellular Calcium Dynamics Permit a Purkinje Neuron Model to Perform Toggle and Gain Computations Upon its Inputs
Without synaptic input, Purkinje neurons can spontaneously fire in a repeating trimodal pattern that consists of tonic spiking, bursting and quiescence. Climbing fiber input (CF) switches Purkinje neurons out of the trimodal firing pattern and toggles them between a tonic firing and a quiescent stat...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2014-08-01
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Series: | Frontiers in Computational Neuroscience |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fncom.2014.00086/full |