Intracellular Calcium Dynamics Permit a Purkinje Neuron Model to Perform Toggle and Gain Computations Upon its Inputs

Without synaptic input, Purkinje neurons can spontaneously fire in a repeating trimodal pattern that consists of tonic spiking, bursting and quiescence. Climbing fiber input (CF) switches Purkinje neurons out of the trimodal firing pattern and toggles them between a tonic firing and a quiescent stat...

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Bibliographic Details
Main Author: Michael David Forrest
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Computational Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncom.2014.00086/full