Anthocyanins Extracted from Oryza sativa L. Prevent Fluorouracil-Induced Nuclear Factor-κB Activation in Oral Mucositis: In Vitro and In Vivo Studies

Anthocyanins Extracted from Oryza sativa L. Prevent Fluorouracil-Induced Nuclear Factor-κB Activation in Oral Mucositis: In Vitro and In Vivo Studies

This study aims to investigate the immunomodulatory effect of anthocyanins (ANTs) from Oryza sativa L. extracts on 5-fluorouracil (5-FU)-induced oral mucositis, using a rat model and oral keratinocytes. ANTs were detected by high-performance liquid chromatography (HPLC)-electrospray ionization mass...

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Bibliographic Details
Main Authors: Salunya Tancharoen, Prana Shakya, Somphong Narkpinit, Pornpen Dararat, Kiyoshi Kikuchi
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
anthocyanin
NF-κB
5-fluorouracil
chemotherapy
oral mucositis
Online Access:http://www.mdpi.com/1422-0067/19/10/2981

Internet

http://www.mdpi.com/1422-0067/19/10/2981

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