Strong In Vivo Inhibition of HIV-1 Replication by Nullbasic, a Tat Mutant

Strong In Vivo Inhibition of HIV-1 Replication by Nullbasic, a Tat Mutant

HIV-1 infection is effectively controlled by antiviral therapy that inhibits virus replication and reduces viral loads below detectable levels in patients. However, therapy interruption leads to viral rebound due to latently infected cells, which serve as a source of continued viral infection. Inter...

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Bibliographic Details
Main Authors: Hongping Jin, Yifan Sun, Dongsheng Li, Min-Hsuan Lin, Mary Lor, Lina Rustanti, David Harrich
Format: Article
Language:English
Published: American Society for Microbiology 2019-08-01
Series:mBio
Subjects:
nullbasic
animal models
antiviral agents
gene transfer
human immunodeficiency virus
Online Access:https://doi.org/10.1128/mBio.01769-19

Internet

https://doi.org/10.1128/mBio.01769-19

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