DJ-1 null dopaminergic neuronal cells exhibit defects in mitochondrial function and structure: involvement of mitochondrial complex I assembly.

DJ-1 null dopaminergic neuronal cells exhibit defects in mitochondrial function and structure: involvement of mitochondrial complex I assembly.

DJ-1 is a Parkinson's disease-associated gene whose protein product has a protective role in cellular homeostasis by removing cytosolic reactive oxygen species and maintaining mitochondrial function. However, it is not clear how DJ-1 regulates mitochondrial function and why mitochondrial dysfun...

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Bibliographic Details
Main Authors: Jun Young Heo, Ji Hoon Park, Soung Jung Kim, Kang Sik Seo, Jeong Su Han, Sang Hee Lee, Jin Man Kim, Jong Il Park, Seung Kiel Park, Kyu Lim, Byung Doo Hwang, Minho Shong, Gi Ryang Kweon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3293835?pdf=render

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http://europepmc.org/articles/PMC3293835?pdf=render

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