Role of proteinuria in the regulation of renal renin-angiotensin system components in unilateral proteinuric rats

Renin-angiotensin system (RAS) overactivity has been implied in progressive renal function loss. We investigated whether changes in the renal expression of RAS components are specifically associated with the proteinuric kidney. Unilateral adriamycin-induced proteinuria was obtained by clamping the l...

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Bibliographic Details
Main Authors: Leo E Deelman, Gerjan Navis, Erik de Boer, Mirian Wietses, Dick de Zeeuw, Robert H Henning
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2003-03-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2003.006