Regulatory T cells in the pathogenesis and healing of chronic human dermal leishmaniasis caused by Leishmania (Viannia) species.

The inflammatory response is prominent in the pathogenesis of dermal leishmaniasis. We hypothesized that regulatory T cells (Tregs) may be diminished in chronic dermal leishmaniasis (CDL) and contribute to healing during treatment.The frequency and functional capacity of Tregs were evaluated at diag...

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Bibliographic Details
Main Authors: Daniel Rodriguez-Pinto, Adriana Navas, Víctor Manuel Blanco, Lady Ramírez, Daniel Garcerant, Adriana Cruz, Noah Craft, Nancy Gore Saravia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3335885?pdf=render