Brain-derived neurotrophic factor (BDNF)-induced tropomyosin-related kinase B (Trk B) signaling is a potential therapeutic target for peritoneal carcinomatosis arising from colorectal cancer.

Brain-derived neurotrophic factor (BDNF)-induced tropomyosin-related kinase B (Trk B) signaling is a potential therapeutic target for peritoneal carcinomatosis arising from colorectal cancer.

Tropomyosin-related receptor kinase B (TrkB) signaling, stimulated by brain-derived neurotrophic factor (BDNF) ligand, promotes tumor progression, and is related to the poor prognosis of various malignancies. We sought to examine the clinical relevance of BDNF/TrkB expression in colorectal cancer (C...

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Bibliographic Details
Main Authors: Koji Tanaka, Yoshinaga Okugawa, Yuji Toiyama, Yasuhiro Inoue, Susumu Saigusa, Mikio Kawamura, Toshimitsu Araki, Keiichi Uchida, Yasuhiko Mohri, Masato Kusunoki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4011754?pdf=render

Internet

http://europepmc.org/articles/PMC4011754?pdf=render

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