The role of time delays in P53 gene regulatory network stimulated by growth factor

In this paper, a delayed mathematical model for the P53-Mdm2 network is developed. The P53-Mdm2 network we study is triggered by growth factor instead of DNA damage and the amount of DNA damage is regarded as zero. We study the influences of time delays, growth factor and other important chemical re...

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Bibliographic Details
Main Authors: Changyong Dai, Haihong Liu, Fang Yan
Format: Article
Language:English
Published: AIMS Press 2020-05-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2020213?viewType=HTML