BRCA promoter methylation in sporadic versus BRCA germline mutation-related breast cancers

Abstract Background In breast cancer, BRCA promoter hypermethylation and BRCA germline mutations are said to occur together rarely, but this property has not yet been translated into a clinical test. Our aim in this study was to investigate the diagnostic value of BRCA1/2 methylation in distinguishi...

Full description

Bibliographic Details
Main Authors: Shoko Vos, Cathy Beatrice Moelans, Paul Joannes van Diest
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Breast Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13058-017-0856-z