Candida albicans suppresses nitric oxide generation from macrophages via a secreted molecule.

Macrophages and neutrophils generate a potent burst of reactive oxygen and nitrogen species as a key aspect of the antimicrobial response. While most successful pathogens, including the fungus Candida albicans, encode enzymes for the detoxification of these compounds and repair of the resulting cell...

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Bibliographic Details
Main Authors: John R Collette, Huaijin Zhou, Michael C Lorenz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3995984?pdf=render