Bioactive Triterpenes of <i>Protium heptaphyllum</i> Gum Resin Extract Display Cholesterol-Lowering Potential

Bioactive Triterpenes of <i>Protium heptaphyllum</i> Gum Resin Extract Display Cholesterol-Lowering Potential

Hypercholesterolemia is one of the major causes of cardiovascular disease, the risk of which is further increased if other forms of dyslipidemia occur. Current therapeutic strategies include changes in lifestyle coupled with drug administration. Statins represent the most common therapeutic approach...

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Bibliographic Details
Main Authors: Giuseppe Mannino, Piera Iovino, Antonino Lauria, Tullio Genova, Alberto Asteggiano, Monica Notarbartolo, Alessandra Porcu, Graziella Serio, Giorgia Chinigò, Andrea Occhipinti, Andrea Capuzzo, Claudio Medana, Luca Munaron, Carla Gentile
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
hypercholesterolemia
gene expression
HMGCR
PCSK9
PPARα
enzymatic activity
Online Access:https://www.mdpi.com/1422-0067/22/5/2664

Internet

https://www.mdpi.com/1422-0067/22/5/2664

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