Ionocytes and CFTR Chloride Channel Expression in Normal and Cystic Fibrosis Nasal and Bronchial Epithelial Cells

Ionocytes and CFTR Chloride Channel Expression in Normal and Cystic Fibrosis Nasal and Bronchial Epithelial Cells

The airway epithelium contains ionocytes, a rare cell type with high expression of Forkhead Box I1 (<i>FOXI1</i>) transcription factor and Cystic Fibrosis Transmembrane conductance Regulator (<i>CFTR</i>), a chloride channel that is defective in cystic fibrosis (CF). Our aim...

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Bibliographic Details
Main Authors: Paolo Scudieri, Ilaria Musante, Arianna Venturini, Daniela Guidone, Michele Genovese, Federico Cresta, Emanuela Caci, Alessandro Palleschi, Marco Poeta, Francesca Santamaria, Fabiana Ciciriello, Vincenzina Lucidi, Luis J. V. Galietta
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
CFTR
cystic fibrosis
ionocytes
airway epithelium
chloride secretion
Online Access:https://www.mdpi.com/2073-4409/9/9/2090

Internet

https://www.mdpi.com/2073-4409/9/9/2090

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