Transcriptional regulatory networks of methanol-independent protein expression in Pichia pastoris under the AOX1 promoter with trans-acting elements engineering

Abstract To explore the differences in the intracellular transcriptional mechanism in carbon-derepressed and wild-type Pichia pastoris strains fed with three different carbon sources. RNA in carbon-derepressed (Δmig1Δmig2Δnrg1-Mit1; Mut) and wild-type (WT) P. pastoris fed with three different carbon...

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Bibliographic Details
Main Authors: Lei Shi, Jinjia Wang, Xiaolong Wang, Yuanxing Zhang, Zhiwei Song, Menghao Cai, Xiangshan Zhou
Format: Article
Language:English
Published: SpringerOpen 2020-03-01
Series:Bioresources and Bioprocessing
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40643-020-00306-w