Kinome-wide RNAi screen implicates at least 5 host hepatocyte kinases in Plasmodium sporozoite infection.

Kinome-wide RNAi screen implicates at least 5 host hepatocyte kinases in Plasmodium sporozoite infection.

Plasmodium sporozoites, the causative agent of malaria, are injected into their vertebrate host through the bite of an infected Anopheles mosquito, homing to the liver where they invade hepatocytes to proliferate and develop into merozoites that, upon reaching the bloodstream, give rise to the clini...

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Bibliographic Details
Main Authors: Miguel Prudêncio, Cristina D Rodrigues, Michael Hannus, Cécilie Martin, Eliana Real, Lígia A Gonçalves, Céline Carret, Robert Dorkin, Ingo Röhl, Kerstin Jahn-Hoffmann, Adrian J F Luty, Robert Sauerwein, Christophe J Echeverri, Maria M Mota
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-11-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18989463/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18989463/?tool=EBI

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