Kinome-wide RNAi screen implicates at least 5 host hepatocyte kinases in Plasmodium sporozoite infection.
Plasmodium sporozoites, the causative agent of malaria, are injected into their vertebrate host through the bite of an infected Anopheles mosquito, homing to the liver where they invade hepatocytes to proliferate and develop into merozoites that, upon reaching the bloodstream, give rise to the clini...
Main Authors: | Miguel Prudêncio, Cristina D Rodrigues, Michael Hannus, Cécilie Martin, Eliana Real, Lígia A Gonçalves, Céline Carret, Robert Dorkin, Ingo Röhl, Kerstin Jahn-Hoffmann, Adrian J F Luty, Robert Sauerwein, Christophe J Echeverri, Maria M Mota |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-11-01
|
Series: | PLoS Pathogens |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18989463/?tool=EBI |
Similar Items
-
Kinome-wide RNAi Screening to Identify Kinases Involved in Post-translational Modification of FUS
by: Liu, Serena E. B.
Published: (2016) -
The Host Protein Aquaporin-9 is Required for Efficient Plasmodium falciparum Sporozoite Entry into Human Hepatocytes
by: Nadia Amanzougaghene, et al.
Published: (2021-06-01) -
A kinome RNAi screen identified AMPK as promoting poxvirus entry through the control of actin dynamics.
by: Theresa S Moser, et al.
Published: (2010-06-01) -
RNAi Screening of the Kinome to Identify Mediators of proliferation and trastuzumab (Herceptin) resistance in HER2 Breast Cancers
by: Lapin, Valentina
Published: (2012) -
RNAi Screening of the Kinome to Identify Mediators of proliferation and trastuzumab (Herceptin) resistance in HER2 Breast Cancers
by: Lapin, Valentina
Published: (2012)